multi N/C 4300 Series The Trace Detector
- Optimum sensitivity at TOC trace levels
- Short measuring times and highest oxidation power due to high-energy UV radiation at 2 wavelengths
- Economical operation thanks to long-lasting components and inexpensive reagents
- Time-saving automation functions for the ultrapure water range
- New intuitive software with live result display
An extremely sensitive and precise UV digestion device, which is ideally suited for ultra-pure water analysis - in the trace range even without persulfate.
TOC trace analysis without oxidizing agents
The highly precise multi N/C 4300 UV is specifically designed for TOC analysis at the ultra-trace level. He is ideal for analyzing boiler feed water in large-scale power plants, water for injection purposes and TOC cleaning validation in the pharmaceutical sector. Equipped with a high-performance UV reactor, all carbon compounds can be digested rapidly and completely, even in difficult matrices such as monitoring of electrolysis baths for electroplating. At the ultra-trace level, the UV reactor enables digestion without persulfate, which makes operation more efficient, avoiding TOC blank interferences. The device can be retrofitted with a solids module for non-catalytic high-temperature combustion.
- TOC analysis at the ultra-trace level thanks to maximum injection volumes of up to 20 mL
- Persulfate-free sample digestion thanks to high-power long-life UV reactor
- High NPOC sample throughput due to parallel purging and measurement
- New intuitive software with live result display and 21 CFR Part 11 compliant pharma module
- Significant time savings thanks to long-term stable calibrations
- Automatic acidification, purging and sample homogenization
- Device can be upgraded for TOC analysis of solids by means of non-catalytic high-temperature combustion
- Five-year warranty for the focus radiation NDIR detector and three-year warranty for the UV reactor
Brochures
| Title | Language | Info |
|---|---|---|
| Flyer Calibration Standard Offering for TOC, AAS, and ICP Devices (EN) | en | PDF, 492 KB |
| Flyer Kalibrierstandards für TOC-, AAS- und ICP-Geräte (DE) | de | PDF, 633 KB |
| Brochure multi N/C x300 Series (DE) | de | PDF, 1 MB |
| Brochure multi N/C x300 Series (EN) | en | PDF, 1 MB |
| Brochure multi N/C x300 Series (KOR) | ko | PDF, 2 MB |
| Flyer multi N/C Software (DE) | de | PDF, 259 KB |
| Flyer multi N/C Software (EN) | en | PDF, 249 KB |
| Brochure multi N/C x300 Series (FR) | fr | PDF, 6 MB |
| Flyer TOCnology made for you (EN) | en | PDF, 495 KB |
| Flyer TOCnology made for Pharma EN | en | PDF, 893 KB |
High performance for wet chemical UV digestion
TOC analysis at the ultra-trace level requires precision and efficiency. Flow injection from the syringe pump combined with the focus radiation NDIR detector enables a low detection limit of 1 µg/L C at the ultra-trace level.
Sample digestion is performed using a long-life high-power UV reactor with two oxidation wavelengths. The particularly high-energy UV radiation at 254 nm and 185 nm oxidizes even extremely stable carbon compounds quickly and completely, and this without any oxidizing agents such as persulfate. Not only does this make operation safer and more economical, it also delivers more accurate results as it avoids distortion of measurement results due to reagent blank values.
The highly sensitive FR NDIR detector, combined with the high radiation intensity of the UV reactor, makes for precise CO2 detection at the trace and ultra-trace level and also makes the device suitable for aggressive matrices.
The Easy Cal function enables stable long-term multi-point calibration from a single stock solution, saving time and effort.
The automation solutions are specifically designed for applications at the ultra-trace level, making sample preparation and analysis more efficient, and they can be tailored to the needs of our customers. Our comprehensive autosampler portfolio enables automatic acidification, parallel purging and magnetic stirring to homogenize samples, as well as external needle rinsing to prevent sample carryover. The EPA sampler allows operation with polymer septa for TOC analysis in ultrapure water. Optimum blank value minimization is achieved by permanent purging of reagents.
TOC solids measurement can be configured using the additional module HT 1300, which offers manual sample introduction via ceramic boats. This is used for non-catalytic high-temperature combustion at up to 1800 °C (with additives) in a ceramic combustion tube.
Manual TIC analysis for solids by direct acid digestion is available with the TIC module.
Product Variants at a Glance
multi N/C 4300 UV
Extremely sensitive TOC analyzer, which is ideally suited for ultrapure water analysis, especially in pharmaceutical applications. High-power UV oxidation also makes it an ideal device for TOC analysis in complicated matrices, where combustion devices reach their limits.
Solids analysis (optional):
- Non-catalytic high-temperature combustion with HT 1300
- Acid digestion module for TIC analysis in solids
No nitrogen analysis
Applications
- Ultrapure water analysis (water for injection - WFI) in pharma industry
- TOC cleaning validation by swab extraction or final rinse method
- Analysis of boiler feed water and condensates in power plants
- Drinking water analysis
- Highly saline or acidic samples such as in electroplating
Products
multi N/C 4300 UV - TOC analyzer (UV digestion)
Extremely sensitive detection, which makes it ideally suited to ultrapure water TOC analysis, especially for pharmaceutical applications. High-power UV oxidation for TOC analysis in complex matrices, where combustion devices reach their limits.
Order number: 450-500.700-2
Applications
Applications
-
TOC Determination in Raw and Drinking Water (EN)
-
TOC Bestimmung in Rohwasser und Trinkwasser (DE)
Applications
-
TOC System Suitability Test According to USP (EN)
-
Cleaning Validation Procedures in the Pharmaceutical Industry by TOC Analysis (EN)
-
Establishing Extractables Testing from Plastic Packaging Materials and Systems for Pharmaceutical Use by TOC Analysis According to USP (EN)
-
TOC Performance Test as per Japanese and Korean Pharmacopoeia
Technical Data
Detector |
Injection Volume |
Sample Supply |
Measuring Time |
Precision |
Parameters |
Optional Parameters |
Digestion Mode |
Gas supply |
Limit of Detection |
Measurement Range |
Dimension (width x depth x height) |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
multi N/C 4300 UV - TOC analyzer (UV digestion) |
Focus Radiation NDIR | 50 - 20000 µL | Flow injection | 3 - 5 min | 1 - 2 % | TC, TIC, TOC, DOC, NPOC, NPOCplus | Solids TC/TOC/TIC | UV wet chemical digestion | Nitrogen 5.0 or Argon 4.6 | 1 µg/L | 0 - 10000 mg/L | 513 mm x 547 mm x 464 mm |
For more information about our products and possible variants, please refer to the technical documents or use our contact form.
Standards
- APHA SM 5310 A, B, C, D
- ASTM D4839
- DIN EN 13137
- DIN EN 1484
- DIN EN 15936
- EP 2.2.44
- EPA 415.1
- EPA 415.3
- EPA 9060A-1
- ISO 10694
- ISO 8245
- JP 2.59
- USP 643
- USP 661.1
- USP 661.2
Order Information
Order number |
Description |
|---|---|
| 450-500.700-2 | multi N/C 4300 UV - TOC analyzer (UV digestion) |
Accessories
| AS vario Autosampler for flow injection TOC/TNb analyzers | 450-900.140 |
| AS vario ER with ext. needle cleaning for multi N/C 3300 and multi N/C 4300 UV | 450-900.148 |
| AS 21hp Autosampler for flow injection TOC/TNb analyzers | 450-900.106 |
| AS 10e Autosampler for flow injection TOC/TNb analyzers | 450-900.111 |
| EPA Sampler with piercing function for flow injection TOC/TNb analyzers | 450-126.693 |
| HT 1300 for multi N/C 4300 UV - solids combustion module for TC/TOC analysis | 450-126.680 |
| TIC solids module manual | 450-126.575 |
Software
multiWin pro - Operation and data evaluation software for TOC/TNb analyzers
Order number: 450-011.500
The new intuitive software multiWin pro is your user cockpit, with all vital information presented on a single screen. It monitors all key system parameters, clearly presents the measurement results and enables comfortable and targeted operation thanks to its automated, user-friendly workflows. It also offers optional data integrity functions in accordance with FDA 21 CRF Part 11.
The software includes the following features:
- Sequence table: Live results update, option to measure a single sample using different methods
- Calibration: Automatic calibration during the measurement sequence with the calibration evaluation applied to subsequent sample measurements
- Easy Cal: Multi-point calibration from a single standard, including blank correction
- Reporting: Data evaluation and generation of result reports during an ongoing sequence; user-specific choice of units
- Conversion functions: Conversion of TOC results into CSB and BSB5 equivalents, TIC values into CO2 levels, and total nitrogen results into total protein contents
- Self-diagnostics: Automatic and permanent leakage monitoring as well as monitoring of input pressure and internal device pressure, tracking of maintenance intervals, furnace and Peltier temperature, as well as detector status (self-check system)
- Data export: Automatic or manual in LIMS, CSV and PDF formats
| Product | Required | Included |
|---|---|---|
| multi N/C 4300 UV - TOC analyzer (UV digestion) (450-500.700-2) |
FDA 21 CFR Part 11 Compliance module for multiWin pro
Order number: 450-011.501
Software module for FDA 21 CFR Part 11 conformity and data integrity
- 21 CFR Part 11-compliant user management with user roles and assignment of individual permissions
- Electronic signatures (3-stage) for release of calibration reports, methods and analysis results
- Active Directory connection
- Audit trail with comprehensive filtering function to track changes made by users
- Configurable password rules
- IQ, OQ and PQ documentation optimized for pharmaceutical applications
- Software validation documentation and service provision by our support team, including certificate
| Product | Required | Included |
|---|---|---|
| multi N/C 4300 UV - TOC analyzer (UV digestion) (450-500.700-2) |
Consumables
| 899-JPPT2SA | JP SST kit, UV, JP performance test kit stabilized with H2SO4 |
| 899-LIN1SA | Linearity test kit, UV, 0.25 mg/L C sucrose for UV digestion TOC systems |
| 899-LIN2SA | Linearity test kit, UV, 0.50 mg/L C sucrose for UV digestion TOC systems |
| 899-CLUVSA | TOC calibration kit 0.6 mg/L C - UV, sucrose solution stabilized with H2SO4 |
| 899-TOCBNS | TOC stock solution para-benzoquinone USP, 100 mg/L C |
| 899-TOCSNS | TOC stock solution sucrose USP, 100 mg/L C |
| 899-USPS1SA | USP TOC SST kit, UV, SST test kit stabilized with H2SO4 |
| 402-007.884 | FAST connector , straight |
| 402-007.508 | FAST connector , straight |
| 402-007.988 | FAST connector straight |
| 402-007.513 | FAST connector, angled |
| 402-810.050 | Halogen absorber filling for halogen absorber U-tube, I.D. 11 mm |
| 402-810.083 | Halogen absorber filling, 11mm 5 refills of the halogen absorber U-tube, I.D. 11 mm |
| 899-00050-0 | Low TOC Alpha Sampling Swabs |
| 402-884.005 | Pump hose for waste pump (peristaltic pump) |
| 402-825.097 | Reagent bottle, 250 ml for phosphoric acid |
| 402-825.095 | Schott bottle 100 mL with screw cap |
| 402-820.076 | Screw cap GL 45 with 3 holes for needles / tubings (for Schott bottle) |
| 402-884.023 | Screw Cap GL 45 with wide hole for Schott bottle 100 mL |
| 402-950.005 | Set of FAST-Connectors , 8 pcs. |
| 402-881.245 | Set of TC prefilter and water trap |
| 402-950.001 | U-tube halogen absorber O.D. 11 mm |
| 402-884.021 | Waste hose TOC with screw joint for basic unit (2 m) |
| 402-825.110 | Collection tray multi N/C - diameter 100 mm, height 50 mm |
| 450-900.224 | Consumables kit for multi N/C4300 UV |
| 402-881.027 | Finger-Tight-Set 1/16" for tube set, PEEK |
| 402-881.026 | Finger-Tight-Set 1/8" for tube set, PEEK |
| 402-950.012 | IC/Condensation vessel for multi N/C 4300 UV |
| 899-TOCC2A | NPOC calibration kit, UV - 0.5 mg/L C, KHP, drinking water calibration |
| 450-900.225 | Preventive maintenance kit for multi N/C 4300 UV |
| 402-825.091 | Reagent bottle 250 mL for sodium peroxo disulfate |
| 402-883.005 | Sample aspiration tube |
| 402-885.016 | Sample aspiration tube with screw joint |
| 402-884.007 | Sample purge tube |
| 402-884.026 | Sample purge tube with screw joint |
| 899-00049-0 | Sample vials 40 mL , clear, TOC<10ppb for EPA sampler |
| 402-825.086 | Screw cap bottle 2.5 L for ultra-pure rinse water supply |
| 402-823.033 | Syringe 25 mL for syringe pump, 9 port |
| 899-TIC1MNS | TIC stock solution 1000 mg/L C Sodium carbonate and sodium hydrogen carbonate 50:50 Mixture |
| 899-W500SA | TOC preparation water, UV stabilized with H2SO4 for UV digestion TOC systems |
| 899-TC1MNS | TOC stock solution 1000 mg/L C Potassium hydrogenphthalate (KHP) |
| 402-890.305 | Tube kit for multi N/C 4300 UV |
| 402-815.076 | Waste container 5 L |
Downloads
The newsletter of Analytik Jena frequently keeps you posted about:
- News
- Trends and developments
- Events